Pharmaceutical Industry and Prescription Drug Warnings
Things you should definitely know about pharmaceutical drugs. Don't just
treat the symptoms, you need to address the causes.
The Marketing of Madness:
mistakes made by Psychiatrists and the Pharmaceutical industry (youtube 1 of 18).
Psychiatry: An Industry Of Death
Ben Goldacre: Battling Bad Science
American Addict (2013)
War on Health - Gary Null's Documentary Exposing the FDA
Science Fraud: The Price for Fame and Fortune
More Health Documentaries
is the practice of widening the diagnostic
boundaries of illnesses
and aggressively promoting their public
awareness in order to expand the markets for treatment. Among
the entities benefiting from selling and delivering treatments
are pharmaceutical companies, physicians, and other professional
or consumer organizations. (scumbag criminals)
Patient Care America
who make 18 million a day,
from $42 million a month to more than $300 million.
is the same as
when a person dies because
they could not afford the medicine they need to live.
Greedy drug company trying to gouge patients in need of Cancer Drugs
Check Prices for prescription drugs vary widely between pharmacies.
Now scumbags are using
Orphan Drug Act of 1983
to charge high prices for needed drugs, while
taking millions of dollars in government incentives and tax credits. When
a drugmaker wins approval of a medicine for an orphan disease, the company
gets seven years of exclusive rights to the marketplace, which means the
FDA won't approve another version to treat that rare disease for seven
years, even if the brand name company's patent has run out.
By salami slicing the disease into subgroups
, it allows them to get
the orphan drug approval with all the government benefits and even some of
the subsidies, to facilitate development of orphan drugs — drugs for rare
diseases such as Huntington's Disease, myoclonus, ALS, Tourette syndrome
and muscular dystrophy which affect small numbers of individuals residing
in the United States.
is a pharmaceutical agent that has been developed specifically to
treat a rare medical condition, the condition itself being referred to as
an orphan disease.
is a disease that affects a small percentage of the
population. Estimated that more than 300 million people worldwide are
living with one of the 7,000 diseases they define as "rare" orphan
"Drug companies are not here to bring health to the population but to
them on one
level for vast amounts of money
, by treating the symptoms and
not addressing the cause."
H.R.6 - 21st Century Cures Act
114th Congress House Bill
Open Payments from Drug Companies
Reverse Settlement Payments or Pay to Delay
criminal practices by the pharmaceutical industry where drug
manufacturers pay competitors not to manufacture generic
versions of their products, so drug manufacturers
can continue to sell over priced drugs and steal millions from
consumers and the elderly.
Almost six million prescriptions for some type of controlled substance were written
last year alone in Connecticut
. That’s almost double the amount
of people who actually live here.
The amount of money the
world spends on prescription drugs could rise to
$1.5 trillion by 2021There were 45 new
drugs approved by the FDA last year and 41 in 2014
. That's more
than double the number that's been approved in 2016, which as of December
5 was just 19 new drugs.
say that nearly 70 percent of Americans are on
at least one prescription drug
, and more than half take two. The
most commonly prescribed are
. Twenty percent of patients are on five or more
prescription medications. Spending on prescription drugs reached
$250 billion in 2009.
Survey found that
119 Million Americans over the age of 12
took prescription psychotherapeutic drugs
. That's 45 percent of the
refers to the use of two or more psychoactive drugs in
combination to achieve a particular effect. In many cases one drug is used
as a base or primary drug, with additional drugs to leaven or compensate
for the side effects of the primary drug and make the experience more
enjoyable with drug synergy effects, or to supplement for primary drug
when supply is low.
the use of four or more medications by a patient, generally adults aged
over 65 years. Polypharmacy is most common in the
, affecting about 40% of
older adults living in their own homes. About 21% of adults with
intellectual disability are also exposed to polypharmacy. Too Many Meds
for the ElderlyNumber Needed to Treat
With Americans now filling four billion
prescriptions a year
children in the U.S. each year end up in the emergency room
after accidental poisonings that involve taking medicine. In 48
percent of cases, kids got into
their grandparents' medicines
Anxiety and Sleeping Pills 'Linked to Dementia'
discovers, develops, produces, and
markets drugs or pharmaceuticals for use as medications. Pharmaceutical
companies may deal in generic or brand medications and medical devices.
They are subject to a variety of laws and regulations that govern the
patenting, testing, safety, efficacy and marketing of drugs.
is the creation of a particular
pharmaceutical product to fit the unique need of a patient. To do this,
compounding pharmacists combine or process appropriate ingredients using
various tools. This may be done for medically necessary reasons, such as
to change the form of the medication from a solid pill to a liquid, to
avoid a non-essential ingredient that the patient is allergic to, or to
obtain the exact dose(s) needed or deemed best of particular active
Prescription Drugs Info
U.S. Companies Losing $10 Billion a Year Due
to Workers' Opioid Abuse
. And no one is getting arrested, just
like the Bankers
At least 100 people die from drug
overdoses every day in the U.S.
More than 36,000 people die from
drug overdoses annually and most of these deaths are caused by
prescription drugs. We have a serious problem when our
treatments cause people to die, Asking for help shouldn't kill
you, or put innocent people and family members in danger. The
misuse and abuse of prescription painkillers was responsible for
more than 475,000 emergency department visits in 2009, a number
that nearly doubled in just five years. Today it is estimated
that 100 million people in the U.S. suffer from chronic pain –
more than the number with diabetes (26 million), heart disease
(16 million) and cancer (12 million). Many who suffer from
will be treated with opioids. It is estimated that 5.1
million Americans abuse painkillers.The Drug War is a
How did a war on drugs not include scumbag Doctors and criminal pharmaceutical companies
when they clearly caused more deaths and more damage? The
justice system is in on these crimes, accessories to murder.
Another problem to solve.
Injury Prevention & Control: Prescription Drug Overdose
America’s Addiction to Opioids: Heroin and Prescription Drug Abuse
The risk for death when prescribed antipsychotics
to control behavioral problems in demented patients
pharmaceutical market analysis firm
, estimates the 2010
revenues for pharmaceuticals to be over $955 billion, and will
exceed $1 trillion dollars by 2013. Big Pharma also shows
revenues of around $300 billion in medical devices in 2012,
and close to $320 billion in 2013. So the total revenues that
will derive just from pharmaceuticals and devices
will be around $1.32 trillion. According to the World Health
Organization, estimated 2013 global revenues for vaccines is
around $24 billion.
TherapyMental Health Evaluation
Serotonin Reuptake Inhibitor
of Internal Medicine
Too Many Meds Given to Senior Citizens
Annals of Internal Medicine
The Human Brain
Is Greed ' the Biggest Killer in Healthcare
Neural networks examine 3D images—thousands of molecules that
might serve as drug candidates—and predict their
blocking the mechanism of a pathogen.
Novartis-MIT Center for Continuous Manufacturing
Knowing when to stop taking medications and preparing a person
for the changes that they may experience when stopping meds.
Adherence to Treatment
Medication Adherence in Children
Non-compliance with Medical Treatment and Teens
Providing more information to the Patient and the Doctor will help make better choices and
Low levels of the "happiness" neurotransmitter, serotonin
Anti-depressants are are only fully effective roughly 30 percent
of the time, and often come with troublesome side effects.
levels that are released and used by the brain
during depressive episodes trigger processes that promote
-- the obsessive negative thinking that is the
. Then, because they facilitate the production of
exacerbate rumination and actually worsen
symptoms of depression, especially at first. Over time, in some
cases, the SSRIs can reverse ruminative processes and reduce
symptoms -- but this is in spite of the medication, not because
of it. As people and physicians become more aware that
antidepressants only work for a limited period of time, and are
less safe than they have been supposed, the use of
antidepressant medications will decline and the use of
Serotonin Theory of Depression
Mental Health Failures
We need to improve and provide better mental health care services.
is an approach to medical practice
intended to optimize decision-making by emphasizing the use of evidence
from well-designed and -conducted Research
is a branch of healthcare science that determines
the safety and effectiveness (efficacy) of medications, devices,
diagnostic products and treatment regimens intended for human use. These
may be used for prevention, treatment, diagnosis or for relieving symptoms
of a disease. Clinical research is different from clinical practice. In
clinical practice established treatments are used, while in clinical
research evidence is collected to establish a treatment.
is the process by which new candidate medications are discovered. Modern
drug discovery involves the identification of screening hits, medicinal
chemistry and optimization of those hits to increase the affinity,
selectivity (to reduce the potential of side effects), efficacy/potency,
metabolic stability (to increase the half-life), and oral bioavailability.
Once a compound that fulfills all of these requirements has been
identified, it will begin the process of drug development prior to
clinical trials. One or more of these steps may, but not necessarily,
involve computer-aided drug design. In the past Drugs were discovered
through identifying the active ingredient from traditional remedies or by
serendipitous discovery. Later chemical libraries of synthetic small
molecules, natural products or extracts were screened in intact cells or
whole organisms to identify substances that have a desirable therapeutic
effect in a process known as classical pharmacology. Since sequencing of
the human genome which allowed rapid cloning and synthesis of large
quantities of purified proteins, it has become common practice
high throughput screening of large compounds libraries against isolated
biological targets which are hypothesized to be disease modifying in a
process known as reverse pharmacology. Hits from these screens are then
tested in cells and then in animals for efficacy.
You should always question
Research Validated Programs
Busting the billion-dollar myth: how to slash the cost of drug development
Follow Up Study
Lost to follow-up
Randomized Controlled Trial
is a type of scientific (often
medical) experiment which aims to reduce bias when testing a new
treatment. The people participating in the trial are randomly allocated to
either the group receiving the treatment under investigation or to a group
receiving standard treatment (or placebo treatment) as the control.
Randomization minimizes selection bias and the different comparison groups
allow the researchers to determine any effects of the treatment when
compared with the no treatment (control) group, while other variables are
kept constant. The RCT is often considered the gold standard for a
clinical trial. RCTs are often used to test the efficacy or effectiveness
of various types of medical intervention and may provide information about
adverse effects, such as drug reactions. Random assignment of intervention
is done after subjects have been assessed for eligibility and recruited,
but before the intervention to be studied begins.
is an experiment in which information about
the test is masked (kept) from the participant, to reduce or eliminate
bias, until after a trial outcome is known. It is understood that bias may
be intentional or unconscious, thus no dishonesty is implied by blinding.
If both tester and subject are blinded, the trial is called a
draws inferences from a sample to a
population where the independent variable is not under the control of the
researcher because of ethical concerns or logistical constraints.
Randomized, double-blind, placebo-controlled trial of the efficacy and
safety of rilonacept in the treatment of systemic juvenile idiopathic
Clinical Trials Results Database
are experiments done in clinical research.
involves repeating a study using the same methods but with different
subjects and experimenters.
refers to a methodological crisis in science in which
scientists have found that the results of many scientific experiments are
difficult or impossible to replicate on subsequent investigation, either
by independent researchers or by the original researchers themselves.
While the crisis has long-standing roots, the phrase was coined in the
early 2010s as part of a growing awareness of the problem. 70% of them
failed to reproduce another scientist's experiments (50% failed to
reproduce their own experiment).
User-Fee Programs for Prescription Drugs
, also known as compassionate use, refers to the use of
an investigational new drug (IND) outside of a clinical trial by patients
with serious or life-threatening conditions who do not meet the enrollment
criteria for the clinical trial in progress
Compassionate Use (FDA)
Treatment and Control Groups
Clinical Research Associate
"It seems that society is a control group for some crazy experiment"
United States Pharmacopeia
is a type of literature review that
collects and critically analyzes multiple research studies or papers. A
review of existing studies is often quicker and cheaper than embarking on
a new study. Researchers use methods that are selected before one or more
research questions are formulated, and then they aim to find and analyze
studies that relate to and answer those questions. Systematic reviews of
randomized controlled trials are key in the practice of evidence-based
is a statistical matching technique that
attempts to estimate the effect of a treatment, policy, or other
intervention by accounting for the covariates that predict receiving the
treatment. PSM attempts to reduce the bias due to confounding variables
that could be found in an estimate of the treatment effect obtained from
simply comparing outcomes among units that received the treatment versus
those that did not.
Number Needed to
is a correlational research study that
involves repeated observations of the same variables over long
periods of time, often many decades.
the study and analysis of the patterns, causes, and effects of
health and disease conditions in defined populations.
"Peer reviews are only as good as the peers
Peers have to be intelligent and free from bias in
order for the feedback to work and to be accurate and
is a computational technique used in
drug discovery to search libraries of small molecules in order to identify
those structures which are most likely to bind to a drug target, typically
a protein receptor or enzyme.
Make your research visible.
Bias in Research
Bias in Research Studies
is a type of bias
occurring in published academic research. It occurs when the outcome of an
experiment or research study influences the decision whether to publish or
otherwise distribute it. Publication bias is of interest because
literature reviews of claims about support for a hypothesis or values for
a parameter will themselves be biased if the original literature is
contaminated by publication bias.
is the selection of individuals, groups or data
for analysis in such a way that proper randomization is not achieved,
thereby ensuring that the sample obtained is not representative of the
population intended to be analyzed. It is sometimes referred to as the
selection effect. The phrase "selection bias" most often refers to the
distortion of a statistical analysis, resulting from the method of
collecting samples. If the selection bias is not taken into account, then
some conclusions of the study may not be accurate.
Lead Time Bias
is the length of time between the detection of a disease (usually based on
new, experimental criteria) and
its usual clinical presentation and
diagnosis (based on traditional criteria). It is the time between early
diagnosis with screening and the time in which diagnosis would have been
made without screening. It is an important factor when evaluating the
effectiveness of a specific test.
Length Time Bias
is a form of selection bias, a statistical distortion of results that can
lead to incorrect conclusions about the data. Length time bias can occur
when the lengths of intervals are analysed by selecting intervals that
occupy randomly chosen points in time or space. That process favors longer
intervals and so skews the data.
is the violation of the standard codes of
scholarly conduct and ethical behavior in professional scientific
But even with the research there is still a lot of corruption in the drug industry because
of falsified research. More than two-thirds of biomedical papers
over the past four decades were the result of
misconduct, not error. More than 67 percent had to be retracted
because of fraud, suspected fraud, fudged data,
fraudulent studies, lying and duplicate publication or
Significant Scientific Agreement
Opinion: Laetrile At Sloan-Kettering - by Eric Merola - Watch
"It's sad knowing that criminals have
manipulated research just for the money, which has caused the
premature death of thousands of people, people who can have been
saved if they had access to valuable information and knowledge,
instead it was covered up and buried."
Results Of Many Clinical Trials Not Being Reported
Only 13 percent of scientists running clinical trials had reported their results.
50% of Academic Papers are Never Read
Trials are Published
Discontinuation and Nonpublication of Randomized Clinical Trials Conducted
Sharing Clinical Trial Data
Sharing Clinical Trial Data
Yale Open Data
is the movement to make scientific research, data and dissemination
accessible to all levels of an inquiring society, amateur
or professional. It encompasses practices such as publishing open
research, campaigning for open access, encouraging scientists to practice
open notebook science, and generally making it easier to publish and
communicate scientific knowledge.
is a type of open data focused on publishing observations and
results of scientific activities available for anyone to analyze and
was a Creative Commons project for designing strategies and tools
for faster, more efficient web-enabled scientific research. The
organization's goals were to identify unnecessary barriers to research,
craft policy guidelines and legal agreements to lower those barriers, and
develop technology to make research data and materials easier to find and
use. Its overarching goal was to speed the translation of data into
discovery and thereby the value of research.
Web of Science
is an online subscription-based scientific
citation indexing service maintained by Thomson Reuters that provides a
comprehensive citation search. It gives access to multiple databases that
reference cross-disciplinary research, which allows for in-depth
exploration of specialized sub-fields within an academic or scientific
Journal Impact Factors
When you hear people saying,
"The Evidence Proves", or, "There Is No
", or, "The Research
Shows", these people are either lying or they are withholding
key information and knowledge that keeps you from fully
understanding the problem. So you have to ask, "What Evidence?"
Where is this Evidence? What
? Show Me! How was this
Who produced the Research? Most research creates more questions
then it actually answers, or worse, it doesn't really apply to
your particular problem. When you hear someone say "There's No
Evidence", what they are actually saying is "I do not have
enough information or knowledge to accurately understand this
". What is the exact
Council Against Health Fraud
Crazy People treating crazy people, now that's just crazy.
America and New Zealand are the only 2 developed countries in the world that allow
Direct to Consumer Advertising
So it's no surprise that 80% of all pharmaceutical drugs are
consumed by Americans, and America is only 5% of the worlds
population. Pharmaceutical companies also spend over 4 billion
dollars on advertising these drugs to Americans, which the
consumer pays for. So Americans are paying to be manipulated and
drugged. So why are we the
Prescription Drug Alternatives
Mom Gets Rid of Food in her Kitchen that She Believes was
Hurting her Family
"Let Food Be Your Medicine and Medicine Be Your Food"
Diagnostic and Statistical Manual of
or Drug Dealers Hand Book for short.
is a drug dealer’s training manual and nothing more.
It is not science, it's only a drug pushers dream. Everyone has
if you look at all the so called symptoms that psychiatrists and
doctors make up. Plus anyone can fake the symptoms, which leads to
Overprescribing of Medications
or just plain corrupted
behavior. It's a felony to sell or use medications without
prescriptions but somehow Doctors are rarely ever arrested. Only
can fully understand
what is happening to the human brain and how the brain is
affected by foods, chemicals, environment and poor education.
Then this information has to be passed on to parents, teachers
and the general public. The
has failed to protect the general public from bogus
pharmaceutical drugs and the claims they make. The FDA is
and part of the drug dealing business. We should
reevaluate the responsibilities of FDA and create a more
responsible agency that is incorruptible and only serves the
publics best interest and not the interests of
. Parents who believe that their child has ADD or
should seek out
Child Development Professionals
instead of Doctors. The drugs that treat ADD or ADHD cause more
damage to the person then actually helping them.
Pharmaceutical Drugs in Public Drinking Water
A vast array of
pharmaceuticals have been found in the drinking water supplies
of at least 41 million Americans,
. (an Associated Press investigation).
Traces of Drugs in Drinking Water
Pharmaceuticals in Drinking Water
does not have any guidelines about pharmaceuticals in
About 90% of the drug is metabolized. Others aren’t
as much, and a lot of the parent compound is
excreted. The undigested drugs and metabolites, the digested
drugs, are either removed from the body as waste or sweat. These
are either flushed down toilets are go down the drain in our
Deaths and Over Doses from Prescription Drugs
month that prescription painkillers caused 15,000 U.S. deaths in
2008, more than triple the 4,000 deaths in 1999. Emergency room
visits related to
abuse have shot from 19,221 in 2000 to 86,258 in
2009, according to the
In Florida alone, hydrocodone caused 910 deaths and contributed
to 1,803 others between 2003 and 2007. The U.S. consumes 99
percent of the world's hydrocodone and 83 percent of its
, according to a 2008 study by the
Narcotics Control Board
Center for Biotechnology Information
About 48,000 women have died from
between 1999 and 2010, an increase of 400
percent over the period.
In 2010, that amounted to about 18 women every day.
For every woman who dies of a prescription painkiller overdose, 30
go to the emergency department for painkiller misuse or abuse.
Although men are still more likely to die of prescription
painkiller overdoses (more than 10,000 deaths in 2010), the gap
between men and women is closing.
Adverse effects of medical treatment resulted in 142,000
deaths in 2013 up from 94,000 deaths in 1990 globally.
Disturbing new research says the
number of U.S. babies born with signs of
Opiate Drug Withdrawal
has tripled in a decade because of a
surge in pregnant women's use of legal and illegal narcotics,
shut down 1,677 illegal
in June 2013.
Another Drug War
So it's OK for legal Pharmacies to Kill?
say's Don't Put Your Health In the Hands of Crooks, but
they don't say which crooks?
Association of Boards of Pharmacy
recently performed an
analysis of more than 10,000 websites, and found that 97% did
not fully comply with state and federal regulations.
Pharmacy Verification Program
As of 2006, there were 58,768
throughout the US. and way over
10,000 online pharmacies in the U.S.
The time, the people, the resources and the billions of dollars used to make
pharmaceutical drugs are just
. It just goes to show you how incredibly
ignorant people are and how horribly victimized the general
public is. People are just
Human Guinea Pigs
for the greedy. If you were to use that
same time, people, resources and money to stop polluting our
drinking water and stop poisoning our foods, while at the same
time improve education quality and quantity, you would have
healthier people and a much healthier planet. Instead you have
corrupt and irresponsible corporations making people drug
addicts while at the same time polluting the earth, which in
turn makes people sicker and even more dependent on drugs. A
viscous and ignorant cycle. And these drugs have so many
that they not only contribute to more
, they also create more diseases and more
sickness that is actually being alleviated by the drugs
themselves. Corporations don’t want to help you, Corporations
don’t want to educate you, Corporations don’t even want to
protect you, Corporations just want your money no matter whom
they kill or whom they injure. Pharmaceutical drugs are an
epidemic and a
Weapon of Mass Destruction
. I’m not saying all drugs are
bad, just 90% of them. The most dangerous criminals are not
behind bars; they are your
Corporate Leaders and the Politicians they
own that they Bought with our Money
Alliance for Human Research Protection
Human Research Protections
Unethical Human Experimentation in the United States
Pharmaceutical Drug Errors5 million errors a year tied to wrong medications; some cause injury and death.
Confirm the spelling of the drug because 1,500 drugs have names so similar
they’ve been confused with one or more other medications.
U.S. outpatient pharmacies filled 3.9 billion 'Legal'
prescriptions in 2009.
A Child Experiences A Medication Error every 8 Minutes.
Most of the medication errors involved liquid
formulations. Errors were highest among children under the age of 1.
Safe Medication Practices
kill around 195,000 Americans each year and costs the
health care system as much as $300 billion annually.
So please ask about what Safety Guidelines and Procedures
that your Hospital
and Doctor follows and request a copy of the procedures and
guidelines so that you can review them to better understand the
decision making and so that you are more aware of your
responsibilities and the responsibilities of the Doctor and
Hospital. It is extremely important that you know what
questions to ask.
Number Needed to Treat
What really happens when you mix medications
? (video and text)
An average of 195,000 people in the USA died due to potentially preventable,
in-hospital medical errors in each of the years 2000, 2001 and 2002
Health Care Fraud and Abuse
Hospital Connect Search
describes the degree to which a patient correctly follows medical advice.
Most commonly, it refers to medication or
drug compliance, but it can
also apply to other situations such as medical device use, self care,
self-directed exercises, or therapy sessions. Both the patient and the
health-care provider affect compliance, and a positive physician-patient
relationship is the most important factor in improving compliance,
although the high cost of prescription medication also plays a major role.
Women and Men have differences when it comes to Medication amounts and types
Women's Health Research
Sex-Based Differences in Drug Activity
Status of Women Data
Sex and Gender-Based Analysis (SGBA)
Scientists uncover a difference between the Sexes
Sex does matter:
Key molecular process in brain is different in
males and females.
Why medicine often has dangerous side effects for women
International Center for Research on Women
UCLA Center for
the Study of Women
of Minority Health Resource Center
He was one of a group of 14 researchers who found that
diversity in biomedical research
often does not reflect the American population.
Racial and Ethnic Minority Populations
Taking Race out of human genetics
you can't make the genetic
conclusions based on someone's race or ancestry. Subordination
of different groups and social groupings based on myths about
their biologic or genetic predispositions is not always
How Racism makes us Sick: David R. Williams
(video and interactive
Looking at married couples who were together
less than 20 years and couples together for more than 50, similarities
were found between partners, like kidney function, total cholesterol
levels, and the strength of their grips, which is a key predictor of
Society of America
Racial Bias in Health Care
Differences in Physicians' Verbal and Nonverbal Communication
With Black and White Patients at the End of Life
Racial Bias May Be Conveyed by Doctors’ Body Language
Patient Centered Communication
Patient-Centered Communication, Ratings of Care, and Concordance
of Patient and Physician Race
Differences between Racial and Ethnic groups in Health Care
Cultural Diversity at the End of Life: Issues and Guidelines for
Heart disease is the leading cause of death for African
African American Health Disparities Compared to Non-Hispanic
Why genetic research must be more diverse, Keolu Fox:
and interactive text)
There are many things that we have available that helps improve
Matcha Green Tea
The Human Brain
or just a
to name a few. So there are many alternatives
that we have that we can research.
is used for treatment of disorders such as
narcolepsy, shift work sleep disorder, and excessive daytime sleepiness
associated with obstructive sleep apnea. It has also seen widespread
off-label use as a purported cognition-enhancing agent.
is an adjunctive therapy (therapy that uses more
than one medication or modality for the treatment) of treatment-resistant
major depressive disorder, which is a term used in clinical psychiatry to
describe cases of major depressive
(MDD) that do not respond adequately to appropriate courses
of at least two antidepressants.
Etherium Monotomic White Gold
flowering plant native to the Horn of Africa and the Arabian Peninsula.
Among communities from these areas, khat chewing has a history as a social
custom dating back thousands of years. Khat contains a monoamine alkaloid
called cathinone, an amphetamine-like stimulant, which is said to cause
excitement, loss of appetite and euphoria.
is a medication used in the palliative
treatment of Alzheimer's disease.
Transcranial Random Noise Stimulation (TRNS)
are drugs, supplements, or other substances that improve cognitive
function, particularly executive functions, memory, creativity, or
motivation, in healthy individuals. Cognitive Enhancer.
Study SkillsLearning Methods
Healthy individuals run the risk of
pushing themselves beyond optimal levels into
hyperdopaminergic and hypernoradrenergic
vitiating the very behaviors they are striving to improve. The
brain doesn’t fully stop developing until age 25 or 30, making
cognitive enhancement potentially risky even for users who are
well into adulthood.
shows you just how incompetent our education system
is. Kids who should be educated are not supposed to be ignorant
about drugs. When students believe
that they're getting an edge using drugs, that means they don't
And if your using something
that will help you pass a test, then you have already failed
yourself, what happens after the test?
I'm sure you would want to keep your good memory, so what will
you be doing in your lifestyle that would help maintain your
good memory? And on top of that you have to remember that most
testing is flawed
, It does not confirm you understand the
knowledge, only that you studied enough to pass a particular
test. And if the test itself is not even asking the right
questions, then your knowledge becomes fragmented, irrelevant
and ineffective. I hope you didn't pay for that, if you did,
got ripped off
Taking drugs to be smarter?
This reminds me of that movie
Bradley Cooper in the end of the movie says something like.....
"If the drug makes you smarter then eventually you should become smart enough
not to need the drug at all."
That of course implies that the person is learning the
right things at the right time, because just having the ability
to learn does not guarantee that you will learn the right things
at the right time, thus you will still be ignorant.
are misleading the public, just like our
"If you're not learning how ignorant you are, then you're not learning."
If someone has been taking Adderall for years to help them
focus, that means that they have not been focusing on how not to
, or, focusing on why they would even need Adderall
in the first place? Focus on that. What's the point of being
interested in things if one of those things isn't you?
Be interested in yourself
Don't confuse personal perception
Just because something is
to you, that doesn't mean that
it's important or not important. And just because something is
interesting to you, that doesn't mean that the thing is important or
not important. What is stimulating to one person, may be dull to
, fun for some,
but not for
Understand the influences of
signal is a pleasure signal, it does not measure
worth or importance. That is why you have a brain, which is to
decide what's important and when it's important. I Like
something, but not because dopamine tells me that I like it.
I would not call Dopamine a reward circuit, but more of an
enhancing circuit of coincidence. When you have to do something
that's important for your health, like eating certain vegetables
that you don't like, your brain will not release dopamine,
mostly because dopamine is not an indicator of right, wrong,
good or bad. I believe that eventually people will learn how to
release dopamine only when something they are doing is
calculated to be right and good. So the dopamine could help encourage positive
behavior and actions. But even then, awareness of our reality
must not be compromised or degraded by hormones or by any other
things such as chemicals, because we'll become more
vulnerable to mistakes. You can't be a slave to feeling good,
when feeling good makes you a slave.
Plants that Reduce Cravings
controls thinking, but reasoning is a skill that requires
regular updates and practicing. And reasoning itself must be
reasoned with, because if you are not reasoning the things that
matter, then being able to reason will not matter.
Feeling bad is not bad, it is a personal
interpretation of a particular moment, feeling bad is not
a measurement of reality.
Sad is OK
, Feeling Good is OK,
and that time and place in Between is the
that we need,
feeling aware and connected, and having a purpose, or a goal.
, but not so positive that you positively stop
Citizen Science - DIY Chemistry
We should be thankful to ordinary people who have educated themselves enough in order to
examine the world. Though we can't say that people experimenting
on their own is more dangerous then the main stream
pharmaceutical industry, but there are still many dangers
we can all get together and share our notes, and share what we
have learned, we won't waste so much time and resources, or kill
lots of people unnecessarily. This is another reason why
improving education is so important. We have learned a lot, now
it's time to put what we have learned into practice.
What's In My
(youtube 1 hour)
What's in my baggie
Britain's Illegal Rave Renaissance: LOCKED OFF
(vice) (youtube 37 mins.)
is a process used to identify substances contained within a
pill, usually illicit substances. With the increased prevalence of drugs
being available in their pure forms, the terms "reagent testing" may also
be used, with the reagents referred to in context simply as "reagent test
Substance Test Kits
Ez Test Kits
is used as a simple spot-test to presumptively
identify alkaloids as well as other compounds. It is composed of a mixture
of formaldehyde and concentrated sulfuric acid, which is dripped onto the
substance being tested.
is a pejorative term for a substance found within other
substances such as food, fuels or chemicals even though it is not allowed
for legal or other reasons.
Adulterated drugs and devices (21 U.S. Code § 351)Just because a drug is legal or pure
does not mean that it's safe
is scientific research conducted, in whole
or in part, by amateur or nonprofessional scientists. Citizen science is
sometimes described as "public participation in scientific research",
participatory monitoring and participatory action research.
Center for Open Science
increase openness, integrity, and reproducibility of scholarly research.
Teens Recreate Key Ingredient in 'Pharma Bro' Drug for Just $20
group of Australian teenagers have cheaply created the active ingredient
in the drug Daraprim, which “Pharma Bro” Martin Shkreli hiked the cost of
by 5,500 percent. Sydney Grammar students recreated 3.7 grams of
Pyrimethamine, the active ingredient in the drug used to treat parasitic
infection in patients with weakened immune systems.
The Deep Web Drug Lab
is a structural or functional analog of a controlled
substance that has been designed to mimic the pharmacological effects of
the original drug, while avoiding classification as illegal and/or
detection in standard drug tests.Mephedrone
is a synthetic stimulant drug of the amphetamine and cathinone classes.
Slang names include drone, M-CAT, White Magic and meow meow. It is
chemically similar to the cathinone compounds found in the khat plant of
eastern Africa. It comes in the form of tablets or a powder, which users
can swallow, snort or inject, producing similar effects to MDMA,
amphetamines and cocaine.
with Doctor Z
Testing Legal Highs could Save Lives
is any pharmaceutical drug product
manufactured in, extracted from, or semisynthesized from biological
sources. Different from totally synthesized pharmaceuticals, they include
vaccines, blood, blood components, allergenics, somatic cells, gene
therapies, tissues, recombinant therapeutic protein, and living cells used
in cell therapy. Biologics can be composed of sugars, proteins, or nucleic
acids or complex combinations of these substances, or may be living cells
or tissues. They (or their precursors or components) are isolated from
living sources—human, animal, plant, fungal, or microbial.
gives us more insight on how drugs can be
customized towards the individual. But it shouldn't just
be about getting high, it should be just enough of the drug to
let the brain explore these new chemical compounds and explore
the effects on the thinking pathways of the brain.
might reveal something beneficial, and other times reveal
nothing beneficial at all. Drugs should be a temporary
adjustment that reveals the persons own
good, and at the same time give the person a short period of
time to analyze the world from a different perspective. Showing
the person another way of thinking, maybe a more suitable way of
processing the information, knowledge and experiences that they
have accumulated in life. And once you have learned this, there
should be no need for the drug, because now you can repeat the
benefits of the drug yourself. The drug should be just a
showing you how
. But most people can't understand this,
another reason why improving
is so important.
"An undisciplined mind, along with the lack
of knowledge, always leads to some form of abuse, whether sought
"Designer drugs have promise, but we also
have all kinds of natural drugs and herbs that we can examine
Artificial Leaf as Mini-Factory for Medicine
Placebos - The Power of the Mind
Besides showing us how ineffective some drugs are, placebos has
accidentally helped us to discover some of the
powers of the
. From research scientists have
found that Positivity and Hope
is beneficial to the mind and the body
because under those conditions the human body releases
that travel all around the body. And
beneficial to the mind and the body because under those
conditions the body does not release beneficial molecules.
The placebo is
to the powers of the human mind. So
a deep breath can be your
be a placebo
, a way to activate your
where ever you are, and also, to make yourself more
aware of any
that you could be experiencing,
because the powers of the mind can also work against us. We still have a lot to learn.
Patients who knowingly took placebos reported 30 percent
less pain and 29 percent reduction in disability compared to control
Convincing yourself that you slept well
tricks your brain into thinking that you did. It's called “Placebo
is able to influence his autonomic nervous system
and immune system at will.
Don't confuse the placebo effect with
Can the human brain
of a drug just by knowing how and why the drug works?
sometimes more effective and
safer then the actual drug?
Power of the Mind
being under estimated and under utilized?
just more proof that the
Power of the Mind
Is believing in
prove that the power of the mind is real?
is the ritualistic practice of prayer and
gestures (such as laying on of hands) that are claimed to elicit divine
intervention in spiritual and physical healing, especially the Christian
practice. Believers assert that the healing of disease and disability can
be brought about by religious faith through prayer and/or other rituals
that, according to adherents, stimulate a divine presence and power.
Belief in such divine intervention is derived from religious belief.
is an event not explicable by natural or scientific
laws. Such an event may be attributed to a supernatural being (a deity),
magic, a miracle worker, a saint or a religious leader.
is an interdisciplinary medical
field exploring the relationships among social, psychological, and
behavioral factors on bodily processes and quality of life in humans and
animals. Some physical diseases are thought to be particularly prone to be
made worse by mental factors such as
is a branch of medical science that applies biological and physiological
principles to clinical practice. The branch especially applies to biology
and physiology. Biomedicine also can relate to many other categories in
health and biological related fields. It has been the dominant health
system for more than a century.
Placebo: Cracking the Code
Lissa Rankin MD : Is There Scientific Proof We Can Heal
Ourselves? at TEDxAmericanRiviera 2012
Natural Mystery: mind over body 1/3
(video) investigations into
the power of mind over the body. touches on many subjects including self
healing (incl. cancer, heavy burns), hypnosis, kung fu, deep free diving,
anesthetic free operations, mental exercise.
Placebo Effects of Caffeine on Cycling Performance
Scientists have identified for the first time the region in the brain
responsible for the "placebo effect" in pain relief
refers to any effect on a person, resulting
from any activity of one or more persons acting as healthcare
professionals or promoting products or services as beneficial to health,
that does not support a goal of the person affected.
was a hypothesized polymerized form of water
that was the subject of much scientific controversy during the late 1960s.
By 1969 the popular press had taken notice and sparked fears of a "polywater
gap" in the USA.
is a parasitic disease caused by Toxoplasma gondii. Infections
with toxoplasmosis usually cause no symptoms in adult humans. Occasionally
there may be a few weeks or months of mild flu-like illness such as muscle
aches and tender lymph nodes. In a small number of people, eye problems
may develop. In those with a weak immune system, severe symptoms such as
seizures and poor coordination may occur. If infected during pregnancy, a
condition known as congenital toxoplasmosis may affect the child.
What's in a Placebo
Drug companies manufacture their own placebos and they are not
required to list the ingredients. An active placebo is one that
is biologically active, rather than inert. Active placebos are
designed to mimic the side-effects of drugs under study.
The Human Brain
is a Chemical Warehouse
, so we don't need more drugs,
we need more education and more awareness.
Drugs manipulate the auto-pilot or natural functions of the
brain, but drugs do not teach us how to manually control our brain, unless the drug was
used to direct us towards a
particular process, so that we can eventually learn how to control it
on our own.
are biologically occurring short chains of
monomers linked by
peptide (amide) bonds.
Knowledge is a Placebo
When love hurts, a placebo can help
Just believing you’re doing
something to help yourself get over your ex can influence brain regions
associated with emotional regulation and lessen the perception of pain.
Mind over Body
Our brains are at the top of the body to remind us of
Mind over Matter
. The mind must be the
. The body effects the mind, so the mind must know
the difference between what is happening in the body and
what is happening in the
You don't want the body to control your thinking
, but you
don't want to ignore the body either. You have to accurately
interpret the messages coming from your body, without having the
messages effect your thinking ability, because then it will be
almost impossible to know what is happening to your body, or to
your mind. Our bodies and minds are sensitive because they have
to be in order to sense changes that might be a danger to us.
But because the mind is sensitive, we have to take extra care
not to get confused between what's happening in the body and
what's happening in the mind. It's usually the body, but if you
don't understand the differences, then you will not be able to
accurately analyze the true nature of what is happening in your
body, or your mind.
Placebo is Latin for "I will please"
"Anything drugs can do I can do better;
I can do anything better than drugs
where people are mysteriously healed just be a placebo effect?
Placebo effect can also work against you, when you worry
or when you believe that bad things will happen to you, your
body will feel this
in a negative way, and you
not benefit from your thinking
People who have
multiple personalities have diseases related to one personality but not
the other personality
So one personality is fine, while the other personality suffers from a
is when a negative expectation of a phenomenon causes
it to have a more negative effect than it otherwise would. A nocebo effect
causes the perception that the phenomenon will have a negative outcome to
actively influence the result. Mental states such as beliefs, expectations
and anticipation can strongly influence the outcome of: disease;
experience of pain; and even success of surgery. Positive expectations
regarding a treatment can result in more positive outcomes and this effect
is known as the placebo effect.
Sudden Unexpected Death Syndrome
is sudden unexpected death
of adolescents and adults, mainly during sleep. Sudden unexpected death
syndrome is rare in most areas around the world.